Principles of organisation Animal tissues, organs and organ systems

Describe the levels of organisation within living organisms
Describe the digestive system and how it works as an organ system (from KS3)

Describe basic features of enzymes (inc rate calculations for chemical reactions)
Describe the lock and key theory as a model of enzyme action and explain how the shape a of the active sites makes the enzyme specific
Explain the effect of temperature and pH on enzymes
Describe the digestive enzymes, including their names, sites of production and actions

Describe how the products of digestion are used
Describe the features and functions of bile and state where it is produced and released from

Required practical 3: use qualitative reagents to test for a range of carbohydrates, lipids and proteins

Required practical 4: investigate the effect of pH on the rate of reaction of amylase enzyme

Describe the structure of the human heart and lungs (inc how lungs are adapted for gaseous exchange)
Explain how the heart moves blood around the body (inc role and position of the aorta, vena cava, pulmonary artery & vein and coronary arteries)

Explain how the natural resting heart rate is controlled and how irregularities can be corrected
Describe the structure and function of arteries, veins and capillaries
Use simple compound measures such as rate and carry out rate calculations for blood flow
Describe blood and identify its different components, inc identifying blood cells from photographs/diagrams
Describe the functions of blood components, including adaptations to function
Describe what happens in coronary heart disease and what statins are used for
Describe and evaluate treatments for coronary heart disease and heart failure (inc drugs, mechanical devices or transplant)
Recall that heart valves can become faulty and describe the consequences of this
Describe how patients can be treated in the case of heart failure

Describe health and the explain causes of ill-health and the relationship between health and disease
Describe how different types of diseases may interact and translate disease incidence information between graphical and numerical forms
Describe what risk factors are and give examples discussing human and financial costs of non communicable diseases at local, national and global levels
Describe what cancer is and explain the difference between benign and malignant tumours
Describe the known risk factors for cancer, including genetic and lifestyle risk factors